The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2019

Filed:

May. 26, 2015
Applicant:

Evonik Röhm Gmbh, Darmstadt, DE;

Inventors:

Rosario Lizio, Dieburg, DE;

Silko Grimm, Rossdorf, DE;

Hans-Ulrich Petereit, Darmstadt, DE;

Matthias Epple, Hattingen, DE;

Gregor Doerdelmann, Haan, DE;

Assignee:

Evonik Röhm GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/88 (2006.01); A61K 9/51 (2006.01); A61K 9/14 (2006.01); A61K 9/50 (2006.01); C12N 15/11 (2006.01); A61K 9/00 (2006.01); A61K 31/7088 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 9/5115 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 9/143 (2013.01); A61K 9/5073 (2013.01); A61K 9/5146 (2013.01); A61K 9/5153 (2013.01); A61K 9/5161 (2013.01); A61K 9/5169 (2013.01); A61K 9/5192 (2013.01); A61K 31/7088 (2013.01); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 15/88 (2013.01); A61K 48/00 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01);
Abstract

The invention refers to a nanoparticle with a diameter which is the maximum in the nanoparticle size distribution, in the range of 10-300 nm, comprising a) a calcium phosphate nanoparticle core a), b) an active ingredient coating b) on the calcium phosphate nanoparticle core a), c) a lactic acid polymer coating c) on the active ingredient coating b), d) a cationic polymer coating d) on the lactic acid polymer coating c) selected from the group of polyethylene-imines, chitosan and human lactoferrin-derived peptides with a length of 14 to 30 amino acids.


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