The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2019

Filed:

Dec. 12, 2014
Applicant:

Biogen MA Inc., Cambridge, MA (US);

Inventors:

Peter Zawaneh, Brookline, MA (US);

Shyam B. Karki, Hillsborough, NJ (US);

Michael Kaufman, Lexington, MA (US);

Cheuk-Yui Leung, Acton, MA (US);

Jinquan Dong, Stoneham, MA (US);

Ernest Quan, East Lyme, CT (US);

Kalyan Vasudevan, Cambridge, MA (US);

Assignee:

Biogen MA Inc., Carmbridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 9/28 (2006.01); A61K 31/225 (2006.01); A61P 25/00 (2006.01); A61K 9/48 (2006.01); A61K 9/50 (2006.01); A61K 31/22 (2006.01); A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0065 (2013.01); A61K 9/0004 (2013.01); A61K 9/14 (2013.01); A61K 9/2027 (2013.01); A61K 9/2031 (2013.01); A61K 9/2054 (2013.01); A61K 9/2086 (2013.01); A61K 9/2846 (2013.01); A61K 9/2853 (2013.01); A61K 9/2866 (2013.01); A61K 9/2886 (2013.01); A61K 9/4808 (2013.01); A61K 9/5026 (2013.01); A61K 9/5031 (2013.01); A61K 9/5042 (2013.01); A61K 9/5047 (2013.01); A61K 9/5073 (2013.01); A61K 31/22 (2013.01);
Abstract

A controlled release dosage form containing monomethyl fumarate, a compound that can be metabolized into monomethyl fumarate in vivo, or a pharmaceutically acceptable salt thereof or combinations thereof, wherein the monomethyl fumarate, a compound that can be metabolized into monomethyl fumarate in vivo, or a pharmaceutically acceptable salt thereof or combinations thereof is delivered to the subject. Also provided is a method of treating a disease or disorder (e.g., multiple sclerosis) by orally administering a controlled release dosage form containing monomethyl fumarate, a compound that can be metabolized into monomethyl fumarate in vivo, or a pharmaceutically acceptable salt thereof or combinations thereof, wherein the monomethyl fumarate, a compound that can be metabolized into monomethyl fumarate in vivo, or a pharmaceutically acceptable salt thereof or combinations thereof.


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