The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2019

Filed:

Mar. 18, 2015
Applicant:

Kyowa Hakko Kirin Co., Ltd, Tokyo, JP;

Inventors:

Yuji Ueno, Sunto-gun, JP;

Takashi Kayashita, Sunto-gun, JP;

Atsushi Ishihara, Sunto-gun, JP;

Masashi Nakakura, Sunto-gun, JP;

Kyoko Yamauchi, Sunto-gun, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 39/395 (2006.01); A61K 47/12 (2006.01); A61K 47/18 (2017.01); C07K 16/18 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0019 (2013.01); A61K 39/39591 (2013.01); A61K 47/12 (2013.01); A61K 47/183 (2013.01); C07K 16/18 (2013.01); C07K 16/2866 (2013.01); C07K 2317/24 (2013.01); C07K 2317/76 (2013.01);
Abstract

The present invention provides a method of suppressing the formation of a soluble association of an antibody in a solution; a method of suppressing the formation of a chemically degraded product of an antibody in a solution; and a method of stabilizing an antibody in a solution. The present invention also provides a solution-type antibody preparation in which the formation of a soluble association is suppressed; a solution-type antibody preparation in which the formation of a chemically degraded product is suppressed; a solution-type antibody preparation in which the formation of a soluble association, the formation of a chemically degraded product and the formation of an insoluble aggregate are suppressed; an agent for suppressing the formation of a soluble association of an antibody; an agent for suppressing the formation of a chemically degraded product of an antibody; and a stabilizing agent for an antibody.


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