The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2019

Filed:

Oct. 25, 2016
Applicant:

The Penn State Research Foundation, University Park, PA (US);

Inventors:

Thomas K. Wood, Port Matilda, PA (US);

Manish Kumar, State College, PA (US);

Thammajun L. Wood, Port Matilda, PA (US);

Assignee:

The Penn State Research Foundation, University Park, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/21 (2006.01); C07K 14/245 (2006.01); A01N 63/02 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 9/14 (2006.01); C12N 1/00 (2006.01); C12N 1/04 (2006.01); C12N 15/70 (2006.01); C12N 15/74 (2006.01); C12N 15/78 (2006.01); C12R 1/01 (2006.01);
U.S. Cl.
CPC ...
A01N 63/02 (2013.01); C07K 14/21 (2013.01); C07K 14/245 (2013.01); C12N 1/00 (2013.01); C12N 1/04 (2013.01); C12N 9/0075 (2013.01); C12N 9/1029 (2013.01); C12N 9/14 (2013.01); C12N 15/70 (2013.01); C12N 15/74 (2013.01); C12N 15/78 (2013.01); C12R 1/01 (2013.01); C12Y 114/13039 (2013.01); C12Y 203/01184 (2013.01); C12Y 303/02003 (2013.01);
Abstract

Biofilms are provided which are capable of regulating their own thickness, reducing contamination and preventing biofouling. Constructs are introduced into bacteria that comprise nucleic acid molecules encoding an autoinducer synthase polypeptide, a transcriptional regulator and a biofilm dispersal protein. Nucleic acid molecules may also be introduced which encode a nitric oxide synthase, an epoxide hydrolase, or both. Biofilms of the bacteria may be used to reduce biofouling and contamination of a surface.


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