The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2019

Filed:

Jun. 06, 2012
Applicants:

Allan Brasier, Galveston, TX (US);

Adrian Recinos, Galveston, TX (US);

John E. Wiktorowicz, League City, TX (US);

Heidi Spratt, Galveston, TX (US);

Hyunsu Ju, League City, TX (US);

Nikos Vasilakis, Galveston, TX (US);

Ernesto E. T. Marquez, Pittsburgh, PA (US);

Marli Tenorio, Recife, BR;

Laura H. V. G. Gil, Recife, BR;

Eduardo Nascimento, Allentown, PA (US);

Inventors:

Allan Brasier, Galveston, TX (US);

Adrian Recinos, Galveston, TX (US);

John E. Wiktorowicz, League City, TX (US);

Heidi Spratt, Galveston, TX (US);

Hyunsu Ju, League City, TX (US);

Nikos Vasilakis, Galveston, TX (US);

Ernesto E. T. Marquez, Pittsburgh, PA (US);

Marli Tenorio, Recife, BR;

Laura H. V. G. Gil, Recife, BR;

Eduardo Nascimento, Allentown, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/564 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6869 (2013.01); G01N 33/564 (2013.01); G01N 33/56983 (2013.01); G01N 33/6851 (2013.01); G01N 2333/185 (2013.01); G01N 2333/47 (2013.01); G01N 2333/4716 (2013.01); G01N 2333/5428 (2013.01); G01N 2333/55 (2013.01); G01N 2333/76 (2013.01); G01N 2800/26 (2013.01); Y02A 50/53 (2018.01);
Abstract

The present invention provides compositions and methods for detecting, analyzing, and identifying biomolecules used to diagnose patient with risk of DHF. More particularly, the invention provides plasma biomarkers including complement factor D to complement factor H (FactorD/FactorH) ratio and levels of one or more of IL2, desmoplakin, and high molecular weight albumin, which are used to detect risk of developing DHF.


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