The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2019

Filed:

May. 25, 2011
Applicants:

Nita Ahuja, Lutherville, MD (US);

Stephen Baylin, Baltimore, MD (US);

James G. Herman, Lutherville, MD (US);

Jeff Wang, Timonium, MD (US);

Vasudev Bailey, Baltimore, MD (US);

MI J. Yi, Laurel, MD (US);

Inventors:

Nita Ahuja, Lutherville, MD (US);

Stephen Baylin, Baltimore, MD (US);

James G. Herman, Lutherville, MD (US);

Jeff Wang, Timonium, MD (US);

Vasudev Bailey, Baltimore, MD (US);

Mi J. Yi, Laurel, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12Q 1/6886 (2018.01); G01N 33/574 (2006.01); C12Q 1/68 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); G01N 33/57407 (2013.01); G01N 33/57419 (2013.01); G01N 33/57423 (2013.01); G01N 33/57438 (2013.01); C12Q 2600/154 (2013.01);
Abstract

The invention provides compositions and methods for detecting a neoplasia (e.g., pancreatic cancer, lung cancer, colon cancer) in a subject sample (e.g., serum, blood, plasma, tissue). In particular embodiments, the invention provides methods for detecting BNC1 and ADAMTS1 promoter methylation in circulating DNA in serum.


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