The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2019

Filed:

Jan. 31, 2017
Applicants:

Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;

Universite DE Lorraine, Nancy, FR;

Centre Hospitalier ET Universitaire DE Nancy (Chu), Nancy, FR;

Universite Paris Diderot-paris 7, Paris, FR;

Universite Paris Descartes, Paris, FR;

Inventors:

Frederic Jaisser, Paris, FR;

Nicolette Farman, Paris, FR;

Antoine Tarjus, Paris, FR;

Patrick Rossignol, Vandoeuvre-les-nancy, FR;

Faiez Zannad, Vandoeuvre-les-nancy, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C12N 15/113 (2010.01); C12N 15/115 (2010.01); A61K 31/7088 (2006.01); A61K 31/7105 (2006.01); G01N 33/573 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 39/3955 (2013.01); C07K 14/47 (2013.01); C07K 16/18 (2013.01); C12N 15/115 (2013.01); G01N 33/573 (2013.01); C07K 2317/76 (2013.01); C12N 2310/11 (2013.01); C12N 2310/12 (2013.01); C12N 2310/14 (2013.01); C12N 2310/16 (2013.01); G01N 2500/04 (2013.01); G01N 2800/325 (2013.01);
Abstract

The present invention relates to methods and pharmaceutical compositions for the treatment of cardiovascular fibrosis. In particular, the present invention relates to an inhibitor of Neutrophil Gelatinase-Associated Lipocalin (NGAL) activity or expression for use in a method for treating or preventing cardiovascular fibrosis in a subject in need thereof.


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