The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2019

Filed:

Dec. 12, 2014
Applicant:

Samsung Life Public Welfare Foundation, Seoul, KR;

Inventors:

Yun Sil Chang, Seoul, KR;

Won Soon Park, Seoul, KR;

Dong Kyung Sung, Seoul, KR;

So Yoon Ahn, Seoul, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0775 (2010.01); A61K 35/28 (2015.01); A61K 35/545 (2015.01); A61K 9/00 (2006.01); A61K 35/51 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0665 (2013.01); A61K 9/0019 (2013.01); A61K 35/28 (2013.01); A61K 35/51 (2013.01); A61K 35/545 (2013.01); C12N 2501/734 (2013.01);
Abstract

The present invention relates to a pharmaceutical composition for treating cerebrovascular diseases including stem cell-derived exosomes as an active ingredient. The stem cell-derived exosomes according to the present invention have superior nerve cell protective effects, such as inhibition of cerebral ventricular distention, reduction of hydrocephalus, and inhibition of nerve cell death and cellular inflammation in an intraventricular hemorrhage (IVH) animal model, and thus, can be useful in treating cerebrovascular diseases including intraventricular hemorrhage, etc.


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