The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2019
Filed:
May. 04, 2018
Applicants:
Board of Regents, the University of Texas System, Austin, TX (US);
Memorial Sloan-kettering Cancer Center, New York, NY (US);
Inventors:
James Allison, New York, NY (US);
Padmanee Sharma, Bellaire, TX (US);
Sergio A. Quezada, Berkhamsted, GB;
Tihui Fu, Houston, TX (US);
Assignees:
MEMORIAL SLOAN-KETTERING CANCER CENTER, New York, NY (US);
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 38/17 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); A61K 38/1709 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); C07K 16/2803 (2013.01); C07K 16/2827 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/73 (2013.01); C07K 2317/74 (2013.01); C07K 2317/75 (2013.01); C07K 2317/76 (2013.01);
Abstract
Agonists to ICOS in combination with a blocking agent to a T cell inhibitory receptor (e.g., CTLA-4, PD-1, etc.) are demonstrated herein to be useful for the treatment of tumors.