The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2019
Filed:
Feb. 26, 2016
Applicant:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Inventors:
Haidong Dong, Rochester, MN (US);
Eugene D. Kwon, Rochester, MN (US);
Svetomir N. Markovic, Rochester, MN (US);
Christopher J. Krco, Rochester, MN (US);
Assignee:
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); C07K 14/705 (2006.01); C12N 15/113 (2010.01); A61K 35/17 (2015.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 45/00 (2013.01); C07K 14/70532 (2013.01); C12N 15/1138 (2013.01); A61K 35/17 (2013.01); C07K 2317/76 (2013.01); C07K 2319/00 (2013.01); C12N 2310/14 (2013.01);
Abstract
This document provides methods and materials involved in treating cancer. For example, methods and materials for identifying a mammal as having an elevated level of PD-1/CD11aCD8 T cells having the potential to exert anti-cancer effects are provided. In addition, methods and materials for identifying a mammal as having an elevated level of PD-1/CD11aCD8 T cells and administering a PD-1 inhibitor to such a mammal are provided.