The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 01, 2019
Filed:
Apr. 03, 2007
Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods
Applicants:
Jeffrey V. Ravetch, New York, NY (US);
Yoshikatsu Kaneko, Niigata, JP;
Nimmerjahn Falk, Erlangen, DE;
Inventors:
Jeffrey V. Ravetch, New York, NY (US);
Yoshikatsu Kaneko, Niigata, JP;
Nimmerjahn Falk, Erlangen, DE;
Assignee:
The Rockefeller University, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/00 (2006.01); C07K 16/06 (2006.01); C07K 16/18 (2006.01); C12P 21/00 (2006.01); G01N 33/68 (2006.01); A61K 47/68 (2017.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); A61K 47/68 (2017.08); C07K 16/06 (2013.01); C07K 16/18 (2013.01); C12P 21/005 (2013.01); G01N 33/6854 (2013.01); A61K 2039/505 (2013.01); C07K 2317/41 (2013.01); C07K 2317/52 (2013.01); C07K 2317/71 (2013.01); C07K 2317/76 (2013.01);
Abstract
The invention provides a polypeptide containing at least one IgG Fc region region, said polypeptide having a higher anti-inflammatory activity and a lower cytotoxic activity as compared to an unpurified antibody and methods of production of such polypeptide.