The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2019

Filed:

Dec. 29, 2014
Applicant:

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;

Inventors:

Hong Liu, Shanghai, CN;

Beili Wu, Shanghai, CN;

Yongtang Zheng, Shanghai, CN;

Xin Xie, Shanghai, CN;

Hualiang Jiang, Shanghai, CN;

Panfeng Peng, Shanghai, CN;

Ronghua Luo, Shanghai, CN;

Jing Li, Shanghai, CN;

Jian Li, Shanghai, CN;

Ya Zhu, Shanghai, CN;

Ying Chen, Shanghai, CN;

Haonan Zhang, Shanghai, CN;

Liumeng Yang, Shanghai, CN;

Yu Zhou, Shanghai, CN;

Kaixian Chen, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); C07D 409/14 (2006.01); C07D 451/04 (2006.01); C07D 401/14 (2006.01); A61K 45/06 (2006.01); A61K 31/46 (2006.01); A61K 31/4545 (2006.01); A61K 31/454 (2006.01);
U.S. Cl.
CPC ...
C07D 519/00 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/46 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 409/14 (2013.01); C07D 451/04 (2013.01);
Abstract

Provided are 1-(3-aminopropyl) substituted cyclic amine compounds as represented by frmula (I), pharmaceutically acceptable salts, enantiomers, diastereoisomers, racemates and mixtures thereof, and a method of synthesizing said 1-(3-aminopropyl) substituted cyclic amine compounds by using aromatic heterocyclic formaldehyde as raw material. Said compounds can be used as CCR 5 antagonist for the treatment of HIV infection.


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