The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2019

Filed:

Dec. 05, 2016
Applicants:

University of Maryland, Baltimore, Baltimore, MD (US);

The United States of America As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventor:

J. Marc Simard, Baltimore, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/57 (2006.01); G01N 33/68 (2006.01); A61K 31/427 (2006.01); A61K 31/565 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/57 (2013.01); G01N 33/6872 (2013.01); A61K 31/427 (2013.01); A61K 31/565 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention concerns protection of an organ or tissue outside of the central nervous system following an ischemic episode. In particular aspects, the invention concerns organ preservation for transplantation, angina pectoris, kidney reperfusion injury, and so forth. In specific embodiments, the organ is subjected to an inhibitor of an NCchannel that is regulated by SUR1. Exemplary inhibitors include sulfonylurea compounds, such as glibenclamide, for example.


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