The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2019

Filed:

Apr. 20, 2017
Applicant:

Zenith Epigenetics Ltd., Calgary, CA;

Inventors:

Shuang Liu, Schenectady, NY (US);

John Frederick Quinn, Albany, NY (US);

Bryan Cordell Duffy, Glenmont, NY (US);

Ruifang Wang, Schenectady, NY (US);

May Xiaowu Jiang, Guilderland, NY (US);

Gregory Scott Martin, Colonie, NY (US);

He Zhao, Madison, CT (US);

Michael Ellis, Clifton Park, NY (US);

Gregory Steven Wagner, Foster City, CA (US);

Peter Ronald Young, San Francisco, CA (US);

Assignee:

Zenith Epigenetics Ltd., Calgary, AB, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4184 (2006.01); A61K 31/422 (2006.01); A61K 31/423 (2006.01); A61K 31/427 (2006.01); A61K 31/428 (2006.01); A61K 31/4439 (2006.01); A61K 45/06 (2006.01); A61K 31/4709 (2006.01); A61K 31/496 (2006.01); A61K 31/497 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 31/454 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4184 (2013.01); A61K 31/422 (2013.01); A61K 31/423 (2013.01); A61K 31/427 (2013.01); A61K 31/428 (2013.01); A61K 31/4439 (2013.01); A61K 31/454 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/497 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01);
Abstract

The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.


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