The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2019

Filed:

Jun. 06, 2008
Applicants:

Bertrand Ducrey, Martigny, CH;

Patrick Garrouste, Saxon, CH;

Catherine Curdy, Riehen, CH;

Marie-anne Bardet, Maracon, CH;

Herve Porchet, Cugy, CH;

Eija Lundstrom, Lutry, CH;

Frederic Heimgartner, Marin-Epagnier, CH;

Inventors:

Bertrand Ducrey, Martigny, CH;

Patrick Garrouste, Saxon, CH;

Catherine Curdy, Riehen, CH;

Marie-Anne Bardet, Maracon, CH;

Herve Porchet, Cugy, CH;

Eija Lundstrom, Lutry, CH;

Frederic Heimgartner, Marin-Epagnier, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 9/19 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0019 (2013.01); A61K 9/1647 (2013.01); A61K 9/19 (2013.01);
Abstract

Pharmaceutical composition made of microparticles for the slow release of an active substance at least during a period covering the 6th month after injection of said composition, said composition comprising a group of microparticles made of a copolymer of the PLGA type which incorporate an active substance in the form of a water insoluble peptide salt; said copolymer furthermore comprising at least 75% of lactic acid and an inherent viscosity between 0.1 and 0.9 dl/g, as measured in chloroform at 25° C. and at a polymer concentration of 0.5 g/dL; said microparticles furthermore having a size distribution defined as follows: —D (v,0.1) is between 10 and 30 micrometers, —D (v,0.5) is between 30 and 70 micrometers, —D (v,0.9) is between 50 and 1 10 micrometers.


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