The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2019

Filed:

Aug. 20, 2014
Applicants:

Jennifer A. Neff, Rancho Santa Margarita, CA (US);

Joseph Mcguire, Corvallis, OR (US);

Pranav Joshi, Bangalore, IN;

Inventors:

Jennifer A. Neff, Rancho Santa Margarita, CA (US);

Joseph McGuire, Corvallis, OR (US);

Pranav R. Joshi, Bangalore, IN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C08L 71/02 (2006.01); A01N 25/10 (2006.01); A01N 25/34 (2006.01); A23L 3/3463 (2006.01); A61K 47/48 (2006.01); C08G 65/334 (2006.01); C08K 9/08 (2006.01); A01N 63/02 (2006.01); A61L 2/232 (2006.01);
U.S. Cl.
CPC ...
A01N 25/10 (2013.01); A01N 25/34 (2013.01); A01N 63/02 (2013.01); A23L 3/3463 (2013.01); A61K 47/48215 (2013.01); A61K 47/48992 (2013.01); C08G 65/3348 (2013.01); C08K 9/08 (2013.01); C08L 71/02 (2013.01); A61L 2/232 (2013.01); C08G 2650/58 (2013.01); C08K 2201/013 (2013.01); C08L 2205/05 (2013.01); Y10T 428/1352 (2015.01); Y10T 428/1376 (2015.01);
Abstract

The invention is based on the recognition that known antimicrobial compounds, such as nisin or other lantibiotics, can be made to form a long lasting antimicrobial surface coating by linking the peptide with a block polymer, such as PLURONIC® F108 or an end group activated polymer (EGAP) in a manner to form a flexible tether and/or entrap the peptide. The entrapped peptide provides antimicrobial action by early release from entrapment while the tethered peptide provides longer lasting antimicrobial protection. Antimicrobial gels and foams may be prepared using the antimicrobial peptide containing block copolymers.


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