The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2018

Filed:

Jun. 11, 2016
Applicant:

Flodesign Sonics, Inc., Wilbraham, MA (US);

Inventors:

Rudolf Gilmanshin, Framingham, MA (US);

Bart Lipkens, Hampden, MA (US);

Assignee:

FloDesign Sonics, Inc., Wilbraham, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01D 43/00 (2006.01); G01N 33/49 (2006.01); C12Q 1/24 (2006.01); G01N 33/574 (2006.01); B01L 3/00 (2006.01); B06B 1/06 (2006.01); B01D 21/28 (2006.01); B03B 1/04 (2006.01); G01N 15/14 (2006.01); A61M 1/36 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
G01N 33/491 (2013.01); B01D 21/283 (2013.01); B01D 43/00 (2013.01); B01L 3/502715 (2013.01); B01L 3/502761 (2013.01); B03B 1/04 (2013.01); B06B 1/0622 (2013.01); C12Q 1/24 (2013.01); G01N 15/1404 (2013.01); G01N 15/1436 (2013.01); G01N 15/1463 (2013.01); G01N 15/1484 (2013.01); G01N 33/574 (2013.01); A61M 1/362 (2014.02); A61M 1/3678 (2014.02); B01L 2200/025 (2013.01); B01L 2200/0647 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0877 (2013.01); B01L 2400/0436 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/149 (2013.01);
Abstract

Devices and methods for inspecting, detecting, isolating, monitoring, characterizing, or separating pathogens in blood containing blood cells are disclosed. The devices include a flow chamber having a solvent inlet, at least one host-fluid inlet, a particulate outlet, at least one residual outlet, and a reflector. The methods include trapping the pathogens in the acoustic standing wave, introducing a solvent into the flow chamber, and removing the pathogens from the device. Devices and methods for inspecting, detecting, isolating, monitoring, characterizing, or separating specialized circulating cells in blood containing blood cells are also disclosed. The devices include a flow chamber having at least one inlet and at least one outlet, and a microscope objective and a cover glass. The methods include driving the transducer to create an acoustic standing wave in the flow chamber and microbubbles in the blood.


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