The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2018
Filed:
Apr. 18, 2013
Siemens Aktiengesellschaft, München, DE;
Siemens Healthcare Diagnostics Holding Gmbh, Eschborn, DE;
Andreas Keller, Püttlingen, DE;
Eckart Meese, Hütschenhausen, DE;
Cord Friedrich Stähler, Hirschberg an der Bergstraße, DE;
Andreas Kappel, Glasshütten, DE;
Petra Leidinger, Wadern, DE;
Christina Backes, Saarbrücken, DE;
Siemens Aktiengesellschaft, Munich, DE;
Abstract
The invention relates to methods for diagnosing multiple sclerosis with miRNA markers. Diagnosis of multiple sclerosis (MS) can be challenging in patients with atypical presentations and during a first neurological deficit possibly related to inflammatory demyelination. Towards the identification of biomarkers for diagnosis of MS, a comprehensive analysis of miRNA expression patterns was obtained. Significantly deregulated miRNAs were identified, which have previously not been related to MS according to the microRNA disease database. These miRNAs could potentially serve as future diagnostic biomarkers for MS and help in diagnosis, monitoring disease activity, and evaluation of treatment responses in patients with MS.