The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2018
Filed:
Jan. 16, 2015
Wave Life Sciences Ltd., Singapore, SG;
Meena, Belmont, MA (US);
David Butler, Medford, MA (US);
Naoki Iwamoto, Brighton, MA (US);
Nenad Svrzikapa, Cambridge, MA (US);
Gregory L. Verdine, Boston, MA (US);
Ivan Zlatev, Cambridge, MA (US);
WAVE LIFE SCIENCES LTD., Singapore, SG;
Abstract
The present invention relates to chirally controlled oligonucleotides of select designs, chirally controlled oligonucleotide compositions, and methods of making and using the same. In some embodiments, a provided chirally controlled oligonucleotide composition provides different cleavage patterns of a nucleic acid polymer than a reference oligonucleotide composition. In some embodiments, a provided chirally controlled oligonucleotide composition provides single site cleavage within a complementary sequence of a nucleic acid polymer.