The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2018
Filed:
Sep. 07, 2016
Applicant:
Catalyst Biosciences, Inc., South San Francisco, CA (US);
Inventors:
Edwin L. Madison, San Francisco, CA (US);
Christopher Thanos, Tiburon, CA (US);
Assignee:
Catalyst Biosciences, Inc., South San Francisco, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/52 (2006.01); A61K 38/36 (2006.01); C12N 9/64 (2006.01); C12N 15/62 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/6437 (2013.01); C12N 15/62 (2013.01); C12Y 304/21021 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01);
Abstract
Nucleic acid encoding modified factor VII polypeptides, vectors and cells containing the nucleic acid, uses of the nucleic acids, methods of making the encoded polypeptides, and methods of treatment are provided. The encoded modified FVII polypeptides include Factor VIIa and other forms of Factor VII. Among the encoded modified FVII polypeptides provided are those that have altered activities, typically altered procoagulant activity, including increased procoagulant activities.