The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2018

Filed:

Apr. 23, 2010
Applicants:

Henry E. Young, Macon, GA (US);

Paul A. Lucas, Poughkeepsie, NY (US);

Inventors:

Henry E. Young, Macon, GA (US);

Paul A. Lucas, Poughkeepsie, NY (US);

Assignee:

ABT HOLDING COMPANY, Cleveland, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/074 (2010.01); C12N 5/077 (2010.01); A61K 35/12 (2015.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0607 (2013.01); C12N 5/0652 (2013.01); A61K 35/12 (2013.01); A61K 48/00 (2013.01); C12N 2502/03 (2013.01); C12N 2510/00 (2013.01);
Abstract

The present invention relates to pluripotent stem cells, particularly to pluripotent embryonic-like stem cells. The invention further relates to methods of purifying pluripotent embryonic-like stem cells and to compositions, cultures and clones thereof. The present invention also relates to a method of transplanting the pluripotent stem cells of the present invention in a mammalian host, such as human, comprising introducing the stem cells, into the host. The invention further relates to methods of in vivo administration of a protein or gene of interest comprising transfecting a pluripotent stem cell with a construct comprising DNA which encodes a protein of interest and then introducing the stem cell into the host where the protein or gene of interest is expressed. The present also relates to methods of producing mesodermal, endodermal or ectodermal lineage-committed cells by culturing or transplantation of the pluripotent stem cells of the present invention.


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