The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2018

Filed:

Jan. 12, 2015
Applicants:

Innate Pharma, S.a., Marseilles, FR;

University of Genova, Genoa, IT;

Inventors:

Alessandro Moretta, Genoa, IT;

Emanuela Marcenaro, Genova-Pegli, IT;

Francois Romagne, Marseilles, FR;

Pascale Andre, Marseilles, FR;

Assignees:

INNATE PHARMA, S.A., Marseilles, FR;

UNIVERSITY OF GENOVA, Genoa, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 45/06 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/2851 (2013.01); G01N 33/56966 (2013.01); A61K 2039/505 (2013.01); A61K 2039/572 (2013.01); C07K 2317/21 (2013.01); C07K 2317/76 (2013.01); G01N 2333/70596 (2013.01); G01N 2500/04 (2013.01);
Abstract

The present invention relates to methods of treating immune disorders, particularly autoimmune or inflammatory disorders, and methods of producing antibodies and other compounds for use in therapeutic strategies for treating such disorders. Generally, the present methods involve the use of antibodies or other compounds that prevent the stimulation of NKG2A receptors on NK cells, leading to the lysis of dendritic cells that contribute to the pathology of the disorders.


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