The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2018

Filed:

Apr. 08, 2016
Applicants:

Ustav Organicke Chemie a Biochemie Av Cr, V.v.i., Prague, CZ;

Fyziologicky Ustav Av Cr, V.v.i., Prague, CZ;

Inventors:

Vaclav Cerovsky, Roztoky, CZ;

Ondrej Nesuta, Opava, CZ;

Vlasta Dudkova, Prague, CZ;

Hana Sychrova, Prague, CZ;

Marie Kodedova, Nehvizdy, CZ;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); A61K 38/00 (2006.01); A61K 38/04 (2006.01); A61K 38/10 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 38/04 (2013.01); A61K 38/00 (2013.01); A61K 38/10 (2013.01);
Abstract

Synthetic analogs of general formula (I-A), where a is Gly, Lys or β-Ala; b is Met, Leu, Nle, Ile, Trp, Val or Phe; c is Ser, Lys, Arg or Orn; d is Ser, Lys, Arg or Orn; e is Leu, Nle, Ile, Trp, Val or Phe; f is Met, Leu, Nle, Ile, Trp, Val or Phe; g is Leu, Nle, Ile or Trp; h is Lys, Arg, Orn or Ala; i is Lys, Arg, Orn or Ala; j is Ile, Leu, Nle or His; k is Lys, Arg, Orn or Ala; where amino acids in all positions may be in D-configuration, and their use for the treatment of topical infections caused by pathogenic bacteria or yeasts.


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