The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2018

Filed:

Feb. 22, 2017
Applicant:

Aziende Chimiche Riunite Angelini Francesco A.c.r.a.f. S.p.a., Rome, IT;

Inventors:

Maria Alessandra Alisi, Rome, IT;

Nicola Cazzolla, Albano Laziale, IT;

Patrizia Dragone, Rome, IT;

Guido Furlotti, Rome, IT;

Caterina Maugeri, Rome, IT;

Rosella Ombrato, San Lorenzo del Vallo, IT;

Francesca Mancini, Nettuno, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/506 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01);
Abstract

The present invention relates to the 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3β) inhibitors and to their use in the treatment of GSK-3β-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; (viii) epilepsies; and (ix) neuropathic pain.


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