The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2018

Filed:

Jun. 30, 2017
Applicant:

Georgetown University, Washington, DC (US);

Inventors:

Eliot M. Rosen, Fairfax, VA (US);

York A. Tomita, Bethesda, MD (US);

Milton Brown, Brookeville, MD (US);

Assignee:

Georgetown University, Washington, DC (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 69/92 (2006.01); C07C 53/136 (2006.01); C07C 57/40 (2006.01); C07C 57/42 (2006.01); C07C 57/50 (2006.01); C07C 69/76 (2006.01); C07C 311/42 (2006.01); C07D 409/14 (2006.01); C07D 405/14 (2006.01); C07D 487/18 (2006.01); C07D 239/42 (2006.01); C07D 249/04 (2006.01); C07D 257/04 (2006.01); C07D 307/33 (2006.01); C07D 317/46 (2006.01); C07D 317/58 (2006.01); C07D 317/68 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07C 69/92 (2013.01); C07C 53/136 (2013.01); C07C 57/40 (2013.01); C07C 57/42 (2013.01); C07C 57/50 (2013.01); C07C 69/76 (2013.01); C07C 311/42 (2013.01); C07D 239/42 (2013.01); C07D 249/04 (2013.01); C07D 257/04 (2013.01); C07D 307/33 (2013.01); C07D 317/46 (2013.01); C07D 317/58 (2013.01); C07D 317/68 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 487/18 (2013.01); C07C 2601/02 (2017.05); C07C 2603/24 (2017.05); C07C 2603/26 (2017.05);
Abstract

The invention encompasses novel compounds and pharmaceutically acceptable salts thereof and compositions including therapeutically or prophylactically effective amounts of such compounds or pharmaceutically acceptable salts thereof. The invention also encompasses methods for treating or preventing diseases and disorders associated with abnormal cell growth, for example, treating or preventing cancer or tumor growth, which methods include administering to a mammal in need thereof a composition comprising a therapeutically or prophylactically effective amount of a compound of the invention or a pharmaceutically acceptable salt thereof.


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