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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10159768 B1

PDFFull Text
Date of Patent:
Dec. 25, 2018

Filed:

Jun. 15, 2017

Multi-layer biodegradable device having adjustable drug release profile

Applicant:

Bioinspire Technologies, Inc., Palo Alto, CA (US);

Inventors:

Dorna Hakimimehr, San Francisco, CA (US);

Kyle Hammerick, San Jose, CA (US);

Assignee:

BioInspire Technologies, Inc., Palo Alto, CA (US);

Attorneys:

Foley & Lardner LLP

Christopher C. Bolten

Nicola A. Pisano

Primary Examiner:

Jeffrey T Palenik

Int. Cl.
CPC ...
A61F 13/15 (2006.01); A61K 9/70 (2006.01); A61L 15/16 (2006.01); A61K 38/36 (2006.01); A61K 35/14 (2015.01); A61B 17/24 (2006.01); A61L 31/04 (2006.01); A61K 9/00 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01); A61K 31/56 (2006.01); A61L 31/02 (2006.01); A61L 31/06 (2006.01); A61L 31/08 (2006.01); A61M 31/00 (2006.01);
U.S. Cl.
CPC ...
A61L 31/046 (2013.01); A61B 17/24 (2013.01); A61K 9/0002 (2013.01); A61K 9/0043 (2013.01); A61K 31/56 (2013.01); A61L 31/028 (2013.01); A61L 31/047 (2013.01); A61L 31/06 (2013.01); A61L 31/08 (2013.01); A61L 31/148 (2013.01); A61L 31/16 (2013.01); A61M 31/002 (2013.01); A61L 2300/41 (2013.01); A61L 2300/416 (2013.01); A61L 2300/606 (2013.01); A61L 2300/608 (2013.01); A61L 2300/61 (2013.01); A61L 2420/08 (2013.01); Y10T 156/10 (2015.01);
Abstract

Methods and apparatus for a biodegradable multi-layer device suitable for medical applications are provided, wherein the device is formed from multiple film-layers configured to have different characteristics from one another such as different release profiles for therapeutic agents, adhesive properties, stiffness properties, and solubility properties. The film-layers may include a solid fibrinogen component. A device having multiple film-layers may take a non-adherent form during delivery to a target location within or on tissue, and thereafter may be exposed to moisture to take an adherent form on the tissue. The device may include a number of additives, including materials to improve the mechanical properties of the device, or one or more therapeutic or contrast agents.

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