The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2018
Filed:
Oct. 05, 2016
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
Yeda Research and Development Co. Ltd. AT the Weizmann Institute of Science, Rehovot, IL;
Universitaet Duisburg-essen, Essen, DE;
Edward H. Schuchman, Haworth, NJ (US);
Erich Gulbins, Essen, DE;
Anthony Futerman, Rehovot, IL;
Yael Pewzner-Jung, Rehovot, IL;
Icahn School of Medicine at Mount Sinai, New York, NY (US);
Yeda Research and Development Co. Ltd. at the Weizmann Institute of Science, Rehovot, IL;
Abstract
The present invention relates to a method for treating or preventing pathogenic infections in a subject having Cystic Fibrosis, COPD, and/or an open wound. This method involves selecting a subject having Cystic Fibrosis, COPD, and/or an open wound and administering to the selected subject a ceramidase under conditions effective to reduce ceramide and to treat or prevent the pathogenic infection. The method also involves the use of a ceramidase in combination with other drugs to reduce infection, reduce ceramide, or improve lung function in Cystic Fibrosis, COPD, and/or open wound patients.