The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2018
Filed:
Dec. 05, 2016
Applicant:
Kappa Bioscience As, Oslo, NO;
Inventors:
Assignee:
KAPPA BIOSCIENCE AS, Oslo, NO;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/661 (2006.01); A61K 31/222 (2006.01); A61K 31/235 (2006.01); C07C 69/78 (2006.01); C07C 69/76 (2006.01); C07C 69/34 (2006.01); C07C 69/017 (2006.01); C07F 9/09 (2006.01); C07C 69/16 (2006.01); C07C 69/28 (2006.01); C07C 69/40 (2006.01); C07F 9/12 (2006.01); C07C 271/22 (2006.01); A61K 31/325 (2006.01);
U.S. Cl.
CPC ...
A61K 31/661 (2013.01); A61K 31/222 (2013.01); A61K 31/235 (2013.01); A61K 31/325 (2013.01); C07C 69/017 (2013.01); C07C 69/16 (2013.01); C07C 69/28 (2013.01); C07C 69/34 (2013.01); C07C 69/40 (2013.01); C07C 69/76 (2013.01); C07C 69/78 (2013.01); C07C 271/22 (2013.01); C07F 9/098 (2013.01); C07F 9/12 (2013.01);
Abstract
The disclosure relates to prodrugs of vitamin K2, in particular prodrugs of MK-7 in which the diketone is converted to a monosubstituted or disubstituted ester type derivative. These compounds are shown to give MK-7 in plasma. The disclosure also relates to methods of treating conditions using prodrugs of vitamin K2.