The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2018

Filed:

Feb. 16, 2017
Applicant:

Alkermes Pharma Ireland Limited, Dublin, IE;

Inventors:

Tarek A. Zeidan, Lexington, MA (US);

David Manser, Keenagh, IE;

Kristopher Perkin, Athlone, IE;

Philip Cresswell, Carlow, IE;

Magali Hickey, Westwood, MA (US);

Brian Steinberg, Arlington, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 31/496 (2006.01); A61K 9/00 (2006.01); A61K 47/10 (2017.01); A61K 47/26 (2006.01); A61K 9/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 9/0019 (2013.01); A61K 9/10 (2013.01); A61K 9/14 (2013.01); A61K 9/145 (2013.01); A61K 9/146 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01);
Abstract

Described herein is a composition comprising: (a) a first population of particles of a first aripiprazole prodrug; and (b) a second population of particles of a second aripiprazole prodrug, different to the first aripiprazole prodrug. At least one of the first and second prodrug populations has a volume based particle size (Dv50) of less than about 1000 nm. Also described herein are methods of treatment using the aforementioned composition, and methods of making the aforementioned composition.


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