The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 25, 2018
Filed:
Mar. 17, 2015
Applicant:
Exelixis, Inc., South San Francisco, CA (US);
Inventors:
Dana T. Aftab, San Rafael, CA (US);
Sriram Naganathan, San Jose, CA (US);
Wei Xu, Danville, CA (US);
Steven Lacy, San Mateo, CA (US);
Assignee:
Exelixis, Inc., Alameda, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); A61K 9/20 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/47 (2013.01); A61K 9/0053 (2013.01); A61K 9/2054 (2013.01);
Abstract
The invention relates to administration of various pharmaceutical formulations of N-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, (cabozantinib) a c-Met inhibitor, and its metabolites, to achieve desirable pharmacokinetic and pharmacodynamic effects.