The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 25, 2018

Filed:

Nov. 05, 2014
Applicants:

Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;

Universite DE Paris—sud, Orsay, FR;

Commissariat a L'energie Atomique ET Aux Energies Alternatives, Paris, FR;

Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;

Universite Paris Descartes, Paris, FR;

Inventors:

Nathalie Cartier-Lacave, Le Kremlin Bicetre, FR;

Jerome Braudeau, Le Kremlin Bicetre, FR;

Nicole Deglon, Fontenay-aux-Roses, FR;

Philippe Hantraye, Fontenay-aux Roses, FR;

Mickael Audrain, Le Kremlin Bicetre, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/00 (2006.01); A01K 67/033 (2006.01); A01K 67/027 (2006.01); C12N 15/85 (2006.01); C12N 15/86 (2006.01); G01N 33/50 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0278 (2013.01); C12N 15/8509 (2013.01); C12N 15/86 (2013.01); G01N 33/5088 (2013.01); A01K 2207/15 (2013.01); A01K 2217/00 (2013.01); A01K 2217/05 (2013.01); A01K 2217/052 (2013.01); A01K 2227/105 (2013.01); A01K 2267/03 (2013.01); A01K 2267/0312 (2013.01); A01K 2267/0318 (2013.01); C07K 14/4711 (2013.01); C12N 2015/8545 (2013.01); C12N 2750/14143 (2013.01); G01N 2333/47 (2013.01);
Abstract

The present invention relates to a vector comprising a nucleic acid sequence that encodes the APP protein and/or the PS1 protein or variants thereof. The invention also relates to a method for inducing the Alzheimer's disease in an animal using the vector of the invention and to animal model having the Alzheimer's disease obtained by said method.


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