The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 18, 2018
Filed:
Dec. 13, 2013
General Electric Company, Schenectady, NY (US);
Ramesh Venkatesan, Bangalore, IN;
Arun Balasubramanian, Bangalore, IN;
Chandan Ramaswamy Atreya, Bangalore, IN;
Ravi Hedge, Bangalore, IN;
Ritika Uppal Mukherjee, Bangalore, IN;
General Electric Company, Schenectady, NY (US);
Abstract
The present invention provides an in-vitro method for detecting the presence of a target substance in a biological sample by magnetic resonance, the method comprising: a) providing a mixture comprising a biological sample and a plurality of magnetic nanoparticles, wherein the magnetic nanoparticles comprise a binding agent capable of binding the target substance when the target substance is present in the biological sample; and b) determining a Trelaxation time corresponding to magnetic nanoparticles that are bound to the target substance (T) in the sample; wherein Tdiffers from the Trelaxation time corresponding to the magnetic nanoparticles that are not bound to the target substance (T), and wherein Tis determined without physically separating magnetic nanoparticles that are bound to the target substance from the magnetic nanoparticles that are not bound to the target substance.