The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 18, 2018
Filed:
Dec. 07, 2015
Applicant:
An2h Discovery Limited, Dublin, IE;
Inventor:
Jennifer Johnston, Mill Valley, CA (US);
Assignee:
AN2H DISCOVERY LIMITED, Dublin, IE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01); A61K 31/4196 (2006.01); A61K 31/519 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/93 (2013.01); A61K 31/4196 (2013.01); A61K 31/519 (2013.01); A61K 38/00 (2013.01); C07K 2319/42 (2013.01); C07K 2319/95 (2013.01); C12Y 603/02019 (2013.01); G01N 2800/28 (2013.01);
Abstract
The present invention is directed to methods and compositions for activating a Parkin ligase by administering to a subject in need thereof a therapeutically effective amount of a compound that disrupts at least one Parkin ligase zinc finger. The present invention is also directed to methods of treating and/or reducing the incidence of diseases or conditions related to the activation of Parkin ligase.