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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10155803 B1

PDFFull Text
Date of Patent:
Dec. 18, 2018

Filed:

Nov. 17, 2016

Multivalent heteromultimer scaffold design and constructs

Applicant:

Zymeworks Inc., Vancouver, CA;

Inventors:

Surjit Bhimarao Dixit, Richmond, CA;

Igor Edmondo Paolo D'Angelo, Port Moody, CA;

David Kai Yuen Poon, Richmond, CA;

Assignee:

ZYMEWORKS INC., Vancouver BC, CA;

Attorney:

Kilpatrick Townsend & Stockton LLP

Primary Examiner:

Karen Cochrane Carlson

Int. Cl.
CPC ...
C07K 14/79 (2006.01); C07K 14/765 (2006.01); C07K 14/47 (2006.01); C07K 14/485 (2006.01); C07K 14/605 (2006.01); C07K 14/76 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); C07K 19/00 (2006.01); C12N 9/64 (2006.01);
U.S. Cl.
CPC ...
C07K 14/765 (2013.01); C07K 14/47 (2013.01); C07K 14/4721 (2013.01); C07K 14/485 (2013.01); C07K 14/605 (2013.01); C07K 14/76 (2013.01); C07K 14/79 (2013.01); C07K 16/283 (2013.01); C07K 16/32 (2013.01); C07K 19/00 (2013.01); C12N 9/6454 (2013.01); C12Y 304/21061 (2013.01); C07K 2317/622 (2013.01); C07K 2319/00 (2013.01); C07K 2319/31 (2013.01);
Abstract

Provided herein are multifunctional heteromer proteins. In specific embodiments is a heteromultimer that comprises: at least two monomeric proteins, wherein each monomeric protein comprises at least one cargo polypeptide, attached to a transporter polypeptide, such that said monomeric proteins associate to form the heteromultimer. These therapeutically novel molecules comprise monomers that function as scaffolds for the conjugation or fusion of therapeutic molecular entities resulting in the creation of bispecific or multivalent molecular species.

Find Patent Forward Citations

Dixit, Surjit. (2018). Multivalent heteromultimer scaffold design and constructs (U.S. Patent No. 10155803). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10155803

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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