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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10155775 B1

PDFFull Text
Date of Patent:
Dec. 18, 2018

Filed:

Feb. 04, 2016

Substituted amino six-membered saturated heteroalicycles as long-acting dpp-iv inhibitors

Applicants:

Centaurus Biopharma Co., Ltd., Beijing, CN;

Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Haizhou District, CN;

Lianyungang Runzhong Pharmaceutical Co., Ltd., Lianyungang, Jiangsu, CN;

Inventors:

Xinhe Xu, Beijing, CN;

Yu Shen, Beijing, CN;

Dengming Xiao, Beijing, CN;

Hong Luo, Beijing, CN;

Yong Peng, Beijing, CN;

Yongxin Han, Beijing, CN;

Aiming Zhang, Lianyungang, CN;

Ling Yang, Lianyungang, CN;

Assignees:

Centaurus Biopharma Co., Ltd., Beijing, CN;

Chia Tai Tianqing Pharmaceutical Co., Ltd., Lianyungang, Jiangsu, CN;

Lianyungang Runzhong Pharmaceutical Co., Ltd., Lianyungang, Jiangsu, CN;

Attorney:

Kilpatrick Townsend & Stockton LLP

Primary Examiner:

Venkataraman Balasubramanian

Int. Cl.
CPC ...
C07D 513/04 (2006.01); C07D 487/04 (2006.01); C07D 495/04 (2006.01); C07D 405/04 (2006.01); A61K 31/542 (2006.01); A61K 31/4162 (2006.01); A61K 31/407 (2006.01); A61K 31/4035 (2006.01); A61P 3/10 (2006.01); A61P 5/50 (2006.01); C07D 513/14 (2006.01); A61P 7/00 (2006.01); A61P 3/04 (2006.01); A61P 1/00 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 513/14 (2013.01); A61K 31/407 (2013.01); A61K 31/4035 (2013.01); A61K 31/4162 (2013.01); A61K 31/542 (2013.01); A61P 1/00 (2018.01); A61P 3/04 (2018.01); A61P 7/00 (2018.01); A61P 25/00 (2018.01); C07D 405/04 (2013.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01);
Abstract

The present application relates to a substituted amino six-membered saturated heteroalicycle represented by formula I as a long-acting DPP-IV inhibitor, a method for preparing the same, a pharmaceutical composition comprising the same, and a use of the same in treating and/or preventing diseases and disorders benefitting from DPP-IV inhibition.

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