The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 18, 2018

Filed:

Oct. 25, 2017
Applicants:

Abbvie Deutschland Gmbh & Co. KG, Wiesbaden, DE;

Abbvie Inc., North Chicago, IL (US);

Inventors:

Ramin Faghih, North Chicago, IL (US);

Achim Moeller, Ludwigshafen, DE;

Michael Ochse, Ludwigshafen, DE;

Frauke Pohlki, Ludwigshafen, DE;

Martin Schmidt, Ludwigshafen, DE;

Kevin Sippy, North Chicago, IL (US);

Sean Turner, Ludwigshafen, DE;

Elizabeth Louise Van Der Kam, Ludwigshafen, DE;

Assignees:

ABBVIE INC., North Chicago, IL (US);

ABBVIE DEUTSCHLAND GMBH & CO. KG, Wiesbaden, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01); C07D 519/00 (2013.01);
Abstract

Compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R, R, R, R, Land Gare as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by positive allosteric modulation of the γ-aminobutyric acid B (GABA-B) receptor. Methods for making the compounds are described. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.


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