The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 18, 2018

Filed:

Jul. 13, 2012
Applicants:

Ju Young Lee, Suwon-si, KR;

Keun-ho Ryu, Seoul, KR;

Jae-sun Kim, Suwon-si, KR;

Yong-hyuk Kim, Suwon-si, KR;

Dong-chul Shin, Suwon-si, KR;

Bong-yong Lee, Seoul, KR;

Sang-hwan Kang, Suwon-si, KR;

Hyun-jung Lee, Seoul, KR;

Hoechul Jung, Seoul, KR;

Young Ah Shin, Yongin-si, KR;

Euisun Park, Yongin-si, KR;

Jaeseung Ahn, Seoul, KR;

Hun-taek Kim, Seoul, KR;

Je Ho Ryu, Seongnam-si, KR;

Inventors:

Ju Young Lee, Suwon-si, KR;

Keun-Ho Ryu, Seoul, KR;

Jae-Sun Kim, Suwon-si, KR;

Yong-Hyuk Kim, Suwon-si, KR;

Dong-Chul Shin, Suwon-si, KR;

Bong-yong Lee, Seoul, KR;

Sang-hwan Kang, Suwon-si, KR;

Hyun-Jung Lee, Seoul, KR;

Hoechul Jung, Seoul, KR;

Young Ah Shin, Yongin-si, KR;

Euisun Park, Yongin-si, KR;

Jaeseung Ahn, Seoul, KR;

Hun-Taek Kim, Seoul, KR;

Je Ho Ryu, Seongnam-si, KR;

Assignee:

TIUMBIO CO., LTD., Seongham-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention provides a novel 2-pyridyl substituted imidazole derivative, or a pharmaceutically acceptable salt or solvate thereof, which selectively inhibits the transforming growth factor-β (TGF-β) type I receptor (ALK5) and/or the activin type I receptor (ALK4); a pharmaceutical composition comprising same as an active ingredient; and a use of the 2-pyridyl substituted imidazole derivative for the manufacture of a medicament for preventing or treating a disease mediated by ALK5 and/or ALK4 receptors in a mammal.


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