The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 18, 2018

Filed:

Nov. 10, 2017
Applicant:

Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;

Inventors:

Matthias Hoffmann, Mittelbiberach, DE;

Georg Dahmann, Biberach an der Riss, DE;

Christian Gnamm, Biberach an der Riss, DE;

Daniel Robert Fandrick, Danbury, CT (US);

John Scott, Abingdon, GB;

Clive McCarthy, Wantage, GB;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); A61K 31/422 (2006.01); A61K 31/416 (2006.01); C07D 403/14 (2006.01); A61K 45/06 (2006.01); C07D 231/56 (2006.01); C07D 405/14 (2006.01); C07D 471/04 (2006.01); C07D 493/04 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); A61K 31/416 (2013.01); A61K 31/437 (2013.01); A61K 45/06 (2013.01); C07D 231/56 (2013.01); C07D 403/12 (2013.01); C07D 405/14 (2013.01); C07D 471/04 (2013.01); C07D 493/04 (2013.01);
Abstract

The invention relates to new substituted heteroaryls of formula 1 or of formula 1' wherein A is either N or CH,wherein Ris selected from the group consisting of —C-alkyl, —C-haloalkyl, F, Br, Cl,wherein Y is selected from —O— or —CH—,and wherein Ris defined as in claim, and the pharmaceutically acceptable salts thereof,and the use of these aforementioned compounds for the treatment of diseases such as asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes, lupus nephritis and rheumatoid arthritis.


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