The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 18, 2018
Filed:
Apr. 15, 2016
Applicant:
General Incorporated Association Tsukuba Global Innovation Promotion Agency, Ibaraki, JP;
Inventors:
Yukio Nagasaki, Ibaraki, JP;
Shinpei Kudo, Ibaraki, JP;
Yuji Hiramatsu, Ibaraki, JP;
Hiroaki Sakamoto, Ibaraki, JP;
Quoc Thang Bui, Ibaraki, JP;
Binh Long Vong, Ibaraki, JP;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/785 (2006.01); A61K 47/10 (2017.01); A61K 47/34 (2017.01); C08L 71/08 (2006.01); C08L 77/04 (2006.01); A61K 38/00 (2006.01); A61K 47/32 (2006.01); A61K 47/36 (2006.01); A61K 47/42 (2017.01);
U.S. Cl.
CPC ...
A61K 31/785 (2013.01); A61K 38/00 (2013.01); A61K 47/10 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01); A61K 47/36 (2013.01); A61K 47/42 (2013.01); C08L 71/08 (2013.01); C08L 77/04 (2013.01); C08L 2203/02 (2013.01);
Abstract
An object of the present invention is to provide a composition that serves as an efficient arginine substrate for inducible NO synthase (iNOS) in tumor. The present invention provides a polyion complex (PIC) of PEG-b-poly(L-Arg) or poly(L-Arg)-b-PEG-b-poly(L-Arg) and a polyanionic polymer, and use thereof.