The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 2018

Filed:

Dec. 06, 2012
Applicant:

Mars, Incorporated;

Inventors:

Alan James Martin, Leicestershire, GB;

Paul Glyn Jones, Leicestershire, GB;

Adrian Watson, Aimargues, FR;

Jan Rothuizen, Utrecht, NL;

Hille Fieten, Utrecht, NL;

Pieter Antonius Jozef Leegwater, Utrecht, NL;

Assignee:

MARS, INCORPORATED, McLean, VA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12Q 1/68 (2018.01); C12Q 1/6883 (2018.01); A01K 67/02 (2006.01); G06F 19/18 (2011.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); A01K 67/02 (2013.01); G06F 19/18 (2013.01); C12Q 2600/124 (2013.01); C12Q 2600/156 (2013.01);
Abstract

The present invention provides a method of testing a dog to determine the susceptibility of the dog to liver copper accumulation, comprising detecting in a sample the presence or absence in the genome of the dog of one or more polymorphisms selected from: (a) Chr22_3167534 (SEQ ID NO: 144), Chr22_3135144 (SEQ ID NO: 145), Chr20_55461150 (SEQ ID NO: 146), ChrX_120879711 (SEQ ID NO: 147), Chr19_6078084 (SEQ ID NO: 148), Chr15_62625262 (SEQ ID NO: 149), Chr14_39437543 (SEQ ID NO: 150), Chr15_62625024 (SEQ ID NO: 151), Chr3_86838677 (SEQ ID NO: 152), Chr24_4011833 (SEQ ID NO: 153), Chr18_60812198 (SEQ ID NO: 154), Chr10_65209946 (SEQ ID NO: 155), and the CGCCCC repeat at chromosome location 22:3135287; (b) one or more polymorphisms in linkage disequilibrium with a said polymorphism (a); and/or (c) Chr32_38904515 (SEQ ID NO: 156), Chr8_4892743 (SEQ ID NO: 157) and Chr8_4880518 (SEQ ID NO: 158).


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