The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 2018

Filed:

Dec. 10, 2014
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Andreas Stahl, Oakland, CA (US);

Kevin Tharp, Oakland, CA (US);

Kevin E. Healy, Oakland, CA (US);

Amit Kumar Jha, Oakland, CA (US);

Judith Kraiczy, Oakland, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/35 (2015.01); C12N 5/0775 (2010.01); C12N 5/077 (2010.01); A61K 9/00 (2006.01); C12N 11/04 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0653 (2013.01); A61K 9/0024 (2013.01); A61K 35/35 (2013.01); C12N 11/04 (2013.01); C12N 2501/734 (2013.01); C12N 2506/1384 (2013.01); C12N 2533/80 (2013.01);
Abstract

The present disclosure provides compositions comprising a hydrogel and a cell adhesion ligand that enhances the differentiation of mesenchymal stem cells into brown adipocytes, and/or enhances the maintenance of brown adipocytes. In some cases, a subject composition includes cells that are embedded within the hydrogel. The present disclosure also provides methods of making and using the subject compositions.


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