The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 2018

Filed:

Feb. 21, 2014
Applicant:

The University of Sheffield, Sheffield, GB;

Inventors:

Irene Canton, Sheffield, GB;

Steven Peter Armes, Sheffield, GB;

Nicholas John Warren, Sheffield, GB;

Harry Moore, Sheffield, GB;

Giuseppe Battaglia, London, GB;

Denis Cecchin, London, GB;

Assignee:

The University of Sheffield, Sheffield, South Yorkshire, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0068 (2013.01); C12N 2533/40 (2013.01); C12N 2539/10 (2013.01);
Abstract

The present invention relates to a medium for storing, preserving, culturing, and/or differentiating stem cells. The medium employs a synthetic thermo-responsive copolymer, dispersed in an aqueous vehicle, which allows the medium to be readily 'switched' between a non-gelatinous (fluid) form and a gelatinous form by simply adjusting temperature across the gelling temperature of the medium. As such, stem cells can be easily captured within a 3D gel matrix by simply mixing the stem cells with the non-gelatinous/fluid form of the medium and then gelling the medium by adjusting the temperature across the gelling temperature of the medium. The stem cells encapsulated within the gelatinous form of the medium may then be preserved for a significant time period before either using the stem cells directly within the medium (e.g. in therapy, or in culturing, differentiation, and such like), or after their extraction from the medium.


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