The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 2018

Filed:

Nov. 08, 2010
Applicants:

John D. Price, Radford, VA (US);

Thomas Piccariello, Blacksburg, VA (US);

Robert A. Oberlender, Blacksburg, VA (US);

Michaela E. Mulhare, Christiansburg, VA (US);

Scott B. Palmer, Wilmette, IL (US);

Inventors:

John D. Price, Radford, VA (US);

Thomas Piccariello, Blacksburg, VA (US);

Robert A. Oberlender, Blacksburg, VA (US);

Michaela E. Mulhare, Christiansburg, VA (US);

Scott B. Palmer, Wilmette, IL (US);

Assignee:

Synthonics, Inc., Blacksburg, VA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 23/00 (2006.01); C07F 9/00 (2006.01); C08B 37/08 (2006.01); C08B 37/00 (2006.01); C07C 229/76 (2006.01);
U.S. Cl.
CPC ...
C07H 23/00 (2013.01); C07C 229/76 (2013.01); C07F 9/005 (2013.01); C08B 37/003 (2013.01); C08B 37/0084 (2013.01);
Abstract

Bismuth-containing compounds include bismuth and a biologically active agent coordinated to the bismuth. The biologically active agent includes at least one heteroatom configured for coordination with the bismuth. Coordination polymers include a polymer matrix that contains a bismuth-containing compound. Methods for modulating a pharmacokinetic property of a biologically active agent include coordinating the biologically active agent to bismuth to form a bismuth-containing compound, and administering the bismuth-containing compound orally to a patient. Methods for treating Parkinson's disease, methods for treating hypothyroidism, methods for treating ulcerative colitis, and methods for treating cancer each include administering a bismuth-containing compound to a patient.


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