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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10150760 B1

PDFFull Text
Date of Patent:
Dec. 11, 2018

Filed:

Apr. 05, 2018

Compounds for use in preparing heterocyclic triazole agonists of the apj receptor

Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Xiaoqi Chen, Palo Alto, CA (US);

Alan C. Cheng, San Francisco, CA (US);

Richard V. Connors, Mesa, AZ (US);

Mikkel V. Debenedetto, Waltham, MA (US);

Paul John Dransfield, Arlington, MA (US);

Zice Fu, Foster City, CA (US);

James S. Harvey, Brookline, MA (US);

Julie Anne Heath, Chico, CA (US);

Jonathan Houze, Cambridge, MA (US);

Ted C. Judd, Granada Hills, CA (US);

David John Kopecky, Washington, DC (US);

Su-Jen Lai, Boston, MA (US);

Zhihua Ma, Lexington, MA (US);

Nobuko Nishimura, West Hills, CA (US);

Steven H. Olson, Millbrae, CA (US);

Vatee Pattaropong, Bedford, MA (US);

Xiaodong Wang, Johns Creek, GA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:

Bernard P. Friedrichsen

Primary Examiner:

Shawquia Jackson

Int. Cl.
CPC ...
C07D 405/14 (2006.01); C07D 403/14 (2006.01); C07D 409/14 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); A61K 45/06 (2006.01); A61K 31/4439 (2006.01); A61K 31/497 (2006.01); A61K 31/506 (2006.01); A61K 31/5383 (2006.01); C07D 498/04 (2006.01); C07D 405/04 (2006.01); C07D 471/04 (2006.01); A61K 31/437 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); A61K 31/437 (2013.01); A61K 31/4439 (2013.01); A61K 31/497 (2013.01); A61K 31/506 (2013.01); A61K 31/5383 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 405/04 (2013.01); C07D 409/14 (2013.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01);
Abstract

Compounds of Formula V, salts thereof, tautomers thereof, and salts of the tautomers have the following structure and are useful compounds in preparing small molecule agonists of the APJ Receptor: where the definitions of the variables are provided herein.

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