The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 2018

Filed:

Aug. 12, 2014
Applicant:

Terumo Kabushiki Kaisha, Tokyo, JP;

Inventors:

Keiko Yamashita, Kanagawa, JP;

Shigenori Nozawa, Kanagawa, JP;

Katsumi Morimoto, Kanagawa, JP;

Kyoko Shimamura, Kanagawa, JP;

Assignee:

TERUMO KABUSHIKI KAISHA, Shibuya-Ku, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 29/16 (2006.01); A61L 29/14 (2006.01); A61L 29/08 (2006.01); A61L 31/16 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61L 29/16 (2013.01); A61K 9/0024 (2013.01); A61L 29/08 (2013.01); A61L 29/148 (2013.01); A61L 31/16 (2013.01); A61K 9/0019 (2013.01); A61L 2300/416 (2013.01); A61L 2300/63 (2013.01);
Abstract

A method of reducing the risk of embolization of peripheral blood vessels by providing a medical device having an expandable member having a drug coating layer which has a crystalline morphological form including a plurality of crystal particles of a water-insoluble drug regularly arranged and uniformly sized on the surface of the medical device, inserting the medical device in peripheral blood vessels, expanding the expandable member, pressing the drug coating layer to a blood vessel wall such that at least part of the plurality of crystal particles are transferred to the blood vessel wall, and deflating the expandable member such that the generation of microparticulates having a size that causes embolization of peripheral blood vessels is suppressed.


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