The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2018
Filed:
Apr. 10, 2017
Applicants:
Vib Vzw, Ghent, BE;
Life Sciences Research Partners Vzw, Leuven, BE;
Universiteit Gent, Ghent, BE;
Inventors:
Marinee Chuah, Lovenjoel, BE;
Thierry Vandendriessche, Lovenjoel, BE;
Pieter De Bleser, Buggenhout, BE;
Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/63 (2006.01); C12N 15/52 (2006.01); A61K 38/48 (2006.01); C07K 14/81 (2006.01); C12N 15/85 (2006.01); C12N 9/64 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0058 (2013.01); A61K 38/4846 (2013.01); C07K 14/8121 (2013.01); C12N 9/644 (2013.01); C12N 15/52 (2013.01); C12N 15/63 (2013.01); C12N 15/85 (2013.01); C12N 15/86 (2013.01); C12Y 304/21022 (2013.01); A61K 48/00 (2013.01); C12N 2750/14143 (2013.01); C12N 2799/025 (2013.01); C12N 2799/027 (2013.01); C12N 2830/008 (2013.01); C12N 2830/15 (2013.01); C12N 2830/85 (2013.01);
Abstract
Described are nucleic acid regulatory elements that are able to enhance liver-specific expression of genes, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. These are particularly useful for applications using gene therapy.