The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2018
Filed:
Dec. 01, 2014
Applicants:
Anthony B. Schryvers, Calgary, CA;
Trevor F. Moraes, Toronto, CA;
Scott Gray-owen, Oakville, CA;
Inventors:
Assignee:
Engineered Antigens Inc., Calgary, Alberta, CA;
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/195 (2006.01); A61K 39/104 (2006.01); A61K 39/095 (2006.01); A61K 39/102 (2006.01); C07K 14/22 (2006.01); C07K 14/285 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/1045 (2013.01); A61K 39/095 (2013.01); A61K 39/102 (2013.01); C07K 14/195 (2013.01); C07K 14/22 (2013.01); C07K 14/285 (2013.01); A61K 2039/523 (2013.01); A61K 2039/70 (2013.01);
Abstract
The disclosure provides immunogenic compositions comprising a polypeptide comprising a C-lobe domain or an N-lobe domain of a HIBP surface receptor protein obtainable from or obtained from a Gram-negative bacterial species. The HIBP surface receptor proteins have been modified in such a manner that they are unable to bind host iron binding protein. Methods of making and using these immunogenic positions to prepare animal and human vaccines are also provided.