The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 2018

Filed:

Dec. 12, 2016
Applicant:

Albert B. Deisseroth, Potomac, MD (US);

Inventor:

Albert B. Deisseroth, Potomac, MD (US);

Assignee:

MicroVAX, LLC, Warrenton, VA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/08 (2006.01); C12N 9/10 (2006.01); C07K 14/705 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/08 (2013.01); C07K 14/70575 (2013.01); C12N 9/1051 (2013.01); A61K 2039/575 (2013.01); C07K 2319/40 (2013.01);
Abstract

This two-step method used in thetoxin transport is a unique method of delivery. The use of a vaccine (TAA/ecdCD40L) for the interdiction of this two-step delivery toxin system to reduce cell death and the death of human subjects is believed to be unique in the area of neutralizing antibodies for protection against the lethal effects of an infectious agent. The proposed composition/vaccine strategy foris to combine and administer at the same time the two compositions/vaccines for Toxin A, the one composition/vaccine for Toxin B and the one vaccine for CDTb to determine the effect of mixing these compositions/vaccines on protecting mice from a lethal dose of. This is believed to be the first time that two different tandem repeats from the contact of a ligand with its cellular receptor have been used to prevent binding of the ligand to its cellular receptor.


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