The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 11, 2018
Filed:
Mar. 20, 2015
Applicant:
The Board of Regents of the University of Texas System, Austin, TX (US);
Inventors:
Joachim Herz, Dallas, TX (US);
Gang Yu, Dallas, TX (US);
Bruce Posner, Dallas, TX (US);
Basar Cenik, Dallas, TX (US);
Assignee:
The Board of Regents of the University of Texas System, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/422 (2006.01); C07D 263/56 (2006.01); C07D 413/14 (2006.01); C07D 413/04 (2006.01); C07D 261/18 (2006.01); C07D 495/04 (2006.01); C07D 209/40 (2006.01); A61K 31/404 (2006.01); A61K 31/42 (2006.01); A61K 31/423 (2006.01); A61K 31/454 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/422 (2013.01); A61K 31/404 (2013.01); A61K 31/42 (2013.01); A61K 31/423 (2013.01); A61K 31/454 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 209/40 (2013.01); C07D 261/18 (2013.01); C07D 263/56 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 495/04 (2013.01);
Abstract
The subject matter described here relates to the use of compounds and methods for the increase of progranulin expression. The methods may take place in vitro, ex vivo such as in isolates from adult mammalian tissue, or in vivo. Compounds and methods described herein may find use in the treatment of frontotemporal dementia.