The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 11, 2018

Filed:

May. 17, 2017
Applicant:

Enanta Pharmaceuticals, Inc., Watertown, MA (US);

Inventors:

Yat Sun Or, Watertown, MA (US);

Xuechao Xing, Wilmington, MA (US);

Ruichao Shen, West Roxbury, MA (US);

Bin Wang, Brighton, MA (US);

Brett Granger, Sudbury, MA (US);

Jun Ma, Belmont, MA (US);

Jing He, Somerville, MA (US);

Jiang Long, Wayland, MA (US);

Yong He, Lexington, MA (US);

Guoqiang Wang, Belmont, MA (US);

Assignee:

Elmore Patent Law Group, P.C., Watertown, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/42 (2006.01); C07D 225/04 (2006.01); C07D 213/127 (2006.01); C07D 261/08 (2006.01); C07C 317/38 (2006.01);
U.S. Cl.
CPC ...
A61K 31/42 (2013.01); C07C 317/38 (2013.01); C07D 213/127 (2013.01); C07D 225/04 (2013.01); C07D 261/08 (2013.01);
Abstract

The present invention provides compounds of Formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds and methods of using these compounds to treat or prevent a disease or disorder mediated by FXR. Specifically, the present invention relates to isoxazole derivatives useful as agonists for FXR and methods for their preparation and use.


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